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GLP-1 Stall? Why Your Body Stops Losing Weight | Dr. Michelle Gordon

Hosts Kim Carlos and Kat Carter talk with obesity medicine specialist Dr. Michelle Gordon about the biological factors behind a GLP-1 weight loss plateau. If you are on a medication like tirzepatide or semaglutide and the scale stops moving, it is driven by a complex neuroendocrine response.

Dr. Gordon explains that the hypothalamus operates like a stubborn thermostat, defending a specific weight set point. When you lose weight, the brain reads the change as a threat and triggers physiological defenses. To prevent further weight loss, the body increases hunger hormones and simultaneously lowers its energy expenditure.

Key topics include:

• The Mechanism of a Stall: A weight plateau occurs at the exact point where your declining daily energy expenditure meets your rising natural hunger signals.
• Menopause and Fat Oxidation: Midlife hormonal shifts cause fat oxidation to drop, which alters metabolic burn rates and shifts fat storage to the stomach.
• The Chronic Disease Reality: Clinical data shows that stopping a GLP-1 medication typically results in regaining about two thirds of the lost weight, proving obesity requires continuous management.
• Muscle Mass Preservation: Rapid weight loss from any method causes muscle loss, making strength training essential to preserve lean muscle and protect long-term functional health.
  
  Connect to Dr. Michelle Gordon:
  
  Substack: https://drmichellegordon.substack.com/
  
  Instagram: https://www.instagram.com/doctormichellegordon/
  
  Facebook: https://www.facebook.com/drmichellegordon/
  
  Practice Website: https://drmichellegordon.com/
  
  LinkedIn: https://www.linkedin.com/in/drmichellegordon/
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  / @theplussidez
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  #Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories
  
  
  
  
  

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The Absolute Lies You’ve Heard About GLP-1s (Ozempic Myths Debunked) [REPLAY]

Are you being lied to about Ozempic, Mounjaro, and Wegovy? In this special replay episode, leading obesity medicine specialists break down the biggest GLP-1 myths taking over your feed. We are reposting this crucial conversation because it is more relevant than ever. With GLP-1 price changes and expanding access options through federal programs like the Medicare GLP-1 Bridge, understanding the real science behind these medications is essential for patient advocacy.

We are sharing a few favorite replay episodes right now while Kim is away on bereavement leave following the loss of her sister. We want to deeply thank our subscribers for staying engaged and supporting the show during this time.

In this episode of The Plus Sidez Podcast, Kat joins Kim to sit down with obesity medicine specialists Dr. Matea Rentea and Dr. Ali Novitzki to help listeners better understand their disease and feel empowered in their healthcare journey.

The Myths We Debunk:

• The Muscle Loss Scare: The data behind weight loss and body composition, explaining why the medication itself is not destroying your lean mass.
• The Willpower Narrative: Why obesity is a genetic, chronic metabolic disease rooted in brain biology, not a failure of personal willpower.
• The Shot-Only Illusion: How the medication works alongside your body's natural satiety signals and gut receptors.
  
  

Obesity Doctor Guidance Shared:

• Metabolic Protection: A practical discussion on utilizing a 10-minute fitness routine and a 100-gram protein framework to maintain lean mass and support insulin sensitivity.
• System Navigation: Insights on navigating insurance barriers, managing prior authorizations, and advocating for proper medical care.

Mental Resilience: Tools to process unsolicited comments about your weight and protect your peace from societal judgment.


Episode Topics:

• Why We Are Replaying This Episode: Prices, Access, and Updates
• The Insurance Landscape: Understanding Prior Authorizations
• Meet the Obesity Medicine Specialists
• Deconstructing the GLP-1 Muscle Loss Narrative
• Strategies for Protecting Your Metabolism
• What the Scales Do Not Show About Insulin Resistance
• Natural Satiety Triggers and Gut Receptors
• Recognizing Obesity as a Biological Chronic Disease
• Addressing Weight Stigma and External Commentary

Subscribe to The Plus Sidez Podcast for science-backed episodes breaking down metabolic health, body recomposition, and the truth about weight loss.

Search Tags
GLP1 lies debunked, Ozempic myths, Mounjaro weight loss journey, Wegovy truth, Zepbound body recomposition, insulin sensitivity hacks, natural GLP1 boosters, treating obesity metabolic disease, plus sidez podcast, dr matea rentea, dr ali novitzki
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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy

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GLP-1 Over 60: Why This Feels Different Now Part 2
***Note: Kim had some sound issues, so we appreciate your patience and grace with her audio this episode.


What does it mean to start GLP-1 treatment later in life… after years of trying to make weight loss work?

In this episode, Kim and Kat talk with Dr. Lindsey Ogle, an obesity specialist, and Deb Cooperman, an obesity care advocate and content creator, about starting GLP-1 treatment in your 60s and why the experience can feel different this time around.

As more adults over 60 explore GLP-1 medications, Deb shares her story openly, from decades of diet culture and early messaging about weight to grief, food noise, and navigating obesity treatment later in life. And we also discuss the upcoming coverage of GLP-1s for obesity on Medicare (and maybe Medicaid) in July 2026. Dr. Ogle helps connect those experiences to the science, including expectations, side effects, protein, muscle preservation, and what support can look like as we age.

What we cover:

- GLP-1 weight loss over 60
- Food noise and obesity beyond willpower
- Diet culture and lifelong messaging around weight
- Grief, stress, and emotional eating
- Protein, muscle preservation, and aging on GLP-1s
- Side effects and realistic expectations

Follow Deb

Follow Dr. Ogle
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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy

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Ro - Telehealth for GLP1 Weight Management and GLP-1

_________________________________________________________________________
***Note: Kim had some sound issues, so we appreciate your patience and grace with her audio this episode.

What does it mean to start GLP-1 treatment later in life… after years of trying to make weight loss work?

In this episode, Kim and Kat talk with Dr. Lindsey Ogle, an obesity specialist, and Deb Cooperman, an obesity care advocate and content creator, about starting GLP-1 treatment in your 60s and why the experience can feel different this time around.

As more adults over 60 explore GLP-1 medications, Deb shares her story openly, from decades of diet culture and early messaging about weight to grief, food noise, and navigating obesity treatment later in life. And we also discuss the upcoming coverage of GLP-1s for obesity on Medicare (and maybe Medicaid) in July 2026. Dr. Ogle helps connect those experiences to the science, including expectations, side effects, protein, muscle preservation, and what support can look like as we age.

What we cover:

- GLP-1 weight loss over 60
- Food noise and obesity beyond willpower
- Diet culture and lifelong messaging around weight
- Grief, stress, and emotional eating
- Protein, muscle preservation, and aging on GLP-1s
- Side effects and realistic expectations

Follow Deb

Follow Dr. Ogle


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_________________________________________________________________________
#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy

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What if millions of women with PCOS were misunderstood for years because the condition was treated mainly as a reproductive disorder instead of a metabolic disease tied to insulin resistance, obesity, hormones, and fertility?

In this episode of The Plus SideZ Podcast, Dr. Melanie Cree, a pediatric endocrinologist, obesity researcher, and PCOS/PMOS expert, explains the recent global consensus to rename PCOS to PMOS, or Polyendocrine Metabolic Ovarian Syndrome, to better reflect the condition’s metabolic and hormonal impact.

Dr. Cree breaks down how delayed diagnosis and outdated understanding may have prevented many patients from getting earlier metabolic treatment and intervention.

We discuss:
Why so many women with PCOS were misunderstood or dismissed
The connection between PCOS, PMOS, insulin resistance, obesity, and fertility

• Why weight gain is not just about willpower
• Adolescent PCOS and why early intervention matters
• GLP-1 medications like semaglutide for PCOS/PMOS
• Emerging research focused on ovulation, fertility, and metabolic health
• How hormones, appetite, and metabolism are connected
• Why the PMOS name change could improve diagnosis and treatment

Dr. Cree also shares information about her ongoing research and studies exploring how GLP-1 medications may help improve metabolic and reproductive health in people with PCOS/PMOS.

Learn more about studies
https://medschool.cuanschutz.edu/pediatrics/sections/endocrinology/endocrinology-research/cree-lab/Cree-Melanie-UCD4665?utm_source=chatgpt.com

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This week, we’re revisiting one of the most powerful conversations in Plus SideZ Podcast history with Rosie O'Donnell.

As Kim takes time away following the loss of her sister, we’re sharing a few meaningful “greatest hits” episodes that continue to resonate deeply with listeners. Thank you for continuing to support, download, watch, and share the podcast during this difficult time. This community means more than you know.

In this replay, Rosie opens up about:

- Lifelong struggles with weight and obesity
- How the media treated her body over the years
- Bariatric surgery and her experience after surgery
- Emotional eating, shame, and public scrutiny
- What it feels like to navigate weight and health over 60
- Her experience with GLP-1 medications and changing obesity treatment

As conversations around GLP-1 medications continue to grow, especially with major Medicare coverage changes expected to expand in July 2026, this episode feels more relevant than ever. For many adults over 60, questions about obesity treatment, metabolism, bariatric surgery, and whether GLP-1s can still work after decades of dieting are finally entering the mainstream.

This episode goes beyond headlines and before-and-after stories. It’s an honest conversation about biology, stigma, survival, and what happens when people living with obesity are finally heard with compassion instead of judgment.

If you’ve ever wondered:

- Do GLP-1 medications work differently over 60?
- Can GLP-1s help after bariatric surgery?
- Why does weight loss feel harder with age?
- How much of obesity is biology versus willpower?

…this conversation is for you.

Listen now wherever you get your podcasts and subscribe to The Plus SideZ Podcast for more conversations that validate lived experience with science, honesty, and empathy.

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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy

Send us Fan Mail!

Support the show

Kim Carlos, Executive Producer

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Ro - Telehealth for GLP1 Weight Management
https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55
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GLP-1 Stopped Working? What’s Really Happening with Dr. Spencer Nadolsky,

While Kim is on bereavement leave, we’re replaying one of our most important conversations. Thank you for continuing to listen and support the show during this time.

We’re bringing this episode back because our audience keeps growing, and many of you may be in a different stage of your journey now. Maybe you’ve hit a plateau, gone months without losing weight, or started wondering, “Is my GLP-1 even working anymore?”

In this replay, we’re joined by Dr. Spencer Nadolsky, obesity specialist and founder of Vineyard, to break down what’s really happening when progress slows or stops.

In this episode, we cover:

• Why your GLP-1 may feel like it “stopped working” and what’s actually happening
• The truth about plateaus, stalls, and going months without weight loss
• Why food noise can come back and what that means
• How dose, metabolic adaptation, and expectations play into progress
• What to know about weight regain and whether this is a “forever” medication
• How to think about goal weight and long-term strategy
• The role of exercise and metabolism as your body changes
• The emotional side, including feeling flat or disconnected

_________________________________________________________________________

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_________________________________________________________________________
#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy

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Use Honest Care to Appeal GLP-1 Denials. Go to HonestCare.com/Kim

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Need help appealing your GLP-1 dials? www.FindHonestCare.com/Kim

______________________________________________________________________

Listener Note:
**IMPORTANT** This episode includes discussions of trauma, family dynamics, narcissistic relationships, and eating disorders. Please take care while listening and choose a time and setting that feels right for you.

Over the past three years, a clear pattern has emerged. Many patients trace their struggles with weight back to childhood, shaped by family dynamics, support, and the ripple effects of diet culture.

GLP-1 medications are changing obesity treatment by addressing biology, and obesity is largely genetic. It is also multifactorial. Factors like stress, trauma, and early environments do not cause obesity on their own, but they can make it harder to manage. Yet this part of the conversation is often missing. While attention is placed on medication or diet and exercise, the impact of lived experience is rarely addressed.

In this episode, we cover:

• How childhood and family dynamics shape long-term patterns
• The impact of stress, trauma, and narcissistic relationships on weight management
• Boundaries, including low contact and no contact, as part of healing
• Why lived experience matters in obesity conversations

This episode is led by co-host and producer Kat Carter, who brings both expertise and personal perspective to a conversation that is often overlooked.

Guest

This episode features insights from Dr. Sherrie Campbell, a licensed psychologist with over two decades of experience specializing in trauma, family dynamics, and helping people set boundaries with toxic relationships.

Learn more at: https://drsherriecampbell.com/

______________________________________________________________________

Join this channel to get access to perks:

/ @theplussidez

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#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1Stories

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