Sophia Dew and Binji Pande speak with Vitalik Buterin about technology, human agency, and how the internet is changing the way people think, build, and relate to the world around them. Drawing from his writings and personal reflections, Buterin discusses how his worldview has evolved over the last decade, from creating Ethereum as a teenager to thinking more deeply about the social and philosophical implications of technology today.

The conversation explores the idea of “sanctuary technology,” systems that provide safety and coordination without removing individual freedom or agency. They also discuss the changing relationship between humans and AI, the risks of over-relying on automated systems, and why actively learning and thinking for yourself may become even more important as AI capabilities improve.

Along the way, Buterin reflects on creativity, community, identity, and the challenge of staying intentional in a world that increasingly pushes people toward autopilot.

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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Ben Horowitz shares lessons from building and scaling companies, drawing on his experience as a founder and CEO. He explains why a founder’s primary responsibility comes down to one thing: delivering the right product at the right time.

The conversation covers how strategy actually develops in practice, why a company’s story is inseparable from its strategy, and how founders should think about hiring, fundraising, and decision-making in fast-changing environments. Horowitz also discusses how AI is reshaping teams, the increasing importance of creativity and relationships, and why roles may evolve toward more generalist “builders.”

He also reflects on navigating uncertainty, the reality of pivots, and why defensibility still comes down to solving hard problems and building meaningful relationships with customers.

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Erin Price-Wright speaks with Turner Caldwell and Drew Baglino about what it will take to close America's critical minerals gap and modernize the power infrastructure that underpins the AI economy. With the US more than 50 years behind China in critical mineral supply and grid infrastructure built on systems designed a century ago, they examine where the real bottlenecks are and how to move faster.

The conversation covers how automation, reinforcement learning, and vertically integrated operations can compress the timelines for mining and refining, and why co-locating supply chains matters more than labor costs in the race to reshore manufacturing. Baglino explains how solid state transformers can replace aging mechanical grid equipment with silicon and software, while Caldwell outlines how Mariana Minerals is applying autonomous systems to remove the know-how bottleneck from critical mineral processing.

They also discuss the lessons both founders carried from Tesla — techno-optimism, appetite for risk, and mission-driven talent — and what durable industrial policy, smarter permitting, and a federal grid investment framework would unlock for American competitiveness.

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