The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence) cover art

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

By: Sam Charrington
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Summary

 Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.All rights reserved Politics & Government Science
Episodes
  • How to Engineer AI Inference Systems with Philip Kiely - #766

    How to Engineer AI Inference Systems with Philip Kiely - #766
    Apr 30 2026
    In this episode, Philip Kiely, head of AI education at Baseten, joins us to unpack the fast-evolving discipline of inference engineering. We explore why inference has become the stickiest and most critical workload in AI, how it blends GPU programming, applied research, and large-scale distributed systems, and where the line sits between inference and model serving. Philip shares how research-to-production can move in hours, not months, and why understanding “the knobs” of inference—batching, quantization, speculation, and KV cache reuse—lets teams design better products and SLAs. We trace the inference maturity journey from closed APIs to dedicated deployments and in-house platforms, discuss GPU lifecycles, and survey today’s runtime landscape, including vLLM, SGLang, and TensorRT LLM. Finally, we look ahead to agents and multimodality, making the case for specialized, workload-specific runtimes when performance and efficiency matter most. The complete show notes for this episode can be found at https://twimlai.com/go/766.
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    55 mins
  • How Capital One Delivers Multi-Agent Systems with Rashmi Shetty - #765

    How Capital One Delivers Multi-Agent Systems with Rashmi Shetty - #765
    Apr 16 2026
    In this episode, Rashmi Shetty, senior director of enterprise generative AI platform at Capital One, joins us to explore how the company is designing, deploying, and scaling multi-agent systems in a highly regulated environment. Rashmi walks us through Chat Concierge, a multi-agent chat experience for auto dealerships that handles intent disambiguation, tool invocation, and human handoffs to deliver safer, more personalized customer journeys. We discuss Capital One’s platform-centric approach to AI agents and how it separates design from runtime governance, embedding policies, guardrails, and cyber controls across agent threat boundaries. Rashmi shares how the team approaches the developer experience for agent builders, observability, and evals for stochastic, multi-agent workflows; and strategies for model specialization, including fine-tuning and distillation. We also cover standards and abstraction, closed-loop learning from production telemetry, and key lessons for enterprises building agentic systems. The complete show notes for this episode can be found at https://twimlai.com/go/765.
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    54 mins
  • The Race to Production-Grade Diffusion LLMs with Stefano Ermon - #764

    The Race to Production-Grade Diffusion LLMs with Stefano Ermon - #764
    Mar 26 2026
    Today, we're joined by Stefano Ermon, associate professor at Stanford University and CEO of Inception Labs to discuss diffusion language models. We dig into how diffusion approaches—traditionally used for images—are being adapted for text and code generation, the technical challenges of applying continuous methods to discrete token spaces, and how diffusion models compare to traditional autoregressive LLMs. Stefano introduces Mercury 2, a commercial-scale diffusion LLM that can generate multiple tokens simultaneously and achieve inference speeds 5-10x faster than small frontier models, paving the way for latency-sensitive applications like voice interactions and fast agentic loops. We also cover the open research challenges in diffusion LLM training, serving infrastructure requirements, and post-training for diffusion-based systems. Finally, Stefano shares his perspective on whether diffusion models can rival or surpass autoregressive LLMs at scale, the advantages for highly controllable generation, and what the future of multimodal diffusion models might look like. The complete show notes for this episode can be found at https://twimlai.com/go/764.
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    1 hr and 3 mins
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Love these shows. Informative and well put together and I always leave a little bit more informed 😬

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