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The Dr. Hyman Show

The Dr. Hyman Show

By: Dr. Mark Hyman
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 Welcome to The Dr. Hyman Show, the podcast helping you take ownership of your health and reimagine what’s possible. Hosted by Dr. Mark Hyman—physician, bestselling author, and pioneer in functional medicine—this show explores the most pressing issues of our time: chronic disease, nutrition, mental health, food policy, prevention, and longevity. In a world where our food system fuels disease and conventional healthcare often overlooks root causes, Dr. Hyman delivers evidence-based insights and expert conversations that empower you to become the CEO of your own health. The Dr. Hyman Show goes beyond the headlines to envision a future where our food and healthcare systems support vitality, reduce chronic disease, and protect the environment. Whether you’re looking for actionable protocols, deeper understanding, or meaningful conversations at the intersection of health, food, and policy, this podcast is your trusted guide. Tune in, take the lead, and transform your health one episode at a time.Dr. Mark Hyman Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • Tired But Wired? The Hidden Loop Destroying Your Energy | Dr. Scott Sherr, MD

    Tired But Wired? The Hidden Loop Destroying Your Energy | Dr. Scott Sherr, MD
    Apr 15 2026
    What if feeling better didn’t have to take months or years to figure out, but could start today? On this episode of The Dr. Hyman Show, I sit down with Dr. Scott Sherr to talk about why so many people feel stuck in what he calls a “sympathetic spiral of doom.” Energy is low, recovery isn’t what it used to be, and there’s a constant sense of stress that doesn’t seem to resolve. We walk through what’s actually happening beneath the surface, why it can be so hard to break out of that pattern once you’re in it, and how to start shifting your energy and recovery. Watch the full conversation on YouTube, or listen wherever you get your podcasts. In this episode, we discuss: • Why you feel “tired but wired” and what it actually means for your body • What’s keeping your energy low even when nothing obvious is wrong • How stress from your life and environment builds up and keeps you stuck • Why calming down doesn’t always work—and what to focus on instead • How to start rebuilding your energy so your body can recover and adapt We shouldn’t have to wait for something to go wrong to take action. The goal is to help your body function better so you can actually feel it day to day. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Perfect Amino, Korrus, Timeline, BON CHARGE, BIOptimizers and Pique. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. (0:00) Introduction and guest Dr. Scott Scherer (3:31) Understanding the sympathetic spiral of doom (5:06) Symptoms and signs of sympathetic overdrive (7:10) Sympathetic activation, mitochondrial function, and stress (10:02) Mitochondria: their role and impact in the body (12:31) Stress, metabolic dysfunction, and their effects (17:43) Nervous system, mitochondria, and the cell danger response (21:25) Survival, stress, and breaking the sympathetic spiral (23:11) Contributors to stress: top-down and bottom-up (25:56) Mitochondria, microbiome, and medication impacts (29:38) Mitochondrial dysfunction and mental health (32:19) Limitations of parasympathetic activation and addressing root causes (36:46) How mitochondrial stress leads to fight-or-flight (37:52) Steps to break the sympathetic spiral and support mitochondria (42:41) Methylene blue: benefits, uses, and safety (50:35) Methylene blue as an MAO inhibitor and for chronic infections (57:17) Case studies, third-party testing, and Transcriptions' evolution (1:02:36) Parasympathetic edge, recovery, and the GABA system (1:07:44) GABA, supplements, and interventions for stress (1:12:23) Addressing root causes and methylene blue usage (1:17:29) Transcriptions products, sleep formula, and practitioner ecosystem (1:19:49) OneBase Health, hyperbaric space, and final information
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    1 hr and 22 mins
  • What It Really Means to Regulate Your Nervous System—and How to Start

    What It Really Means to Regulate Your Nervous System—and How to Start
    Apr 13 2026
    If you’re doing everything “right”—eating well, taking supplements, working on your health—but still feel stuck, this might be the missing piece. Your body cannot heal if it thinks it’s under threat. In this episode, we unpack why your nervous system may be the hidden driver behind inflammation, hormone imbalance, weight gain, and more—and how to finally shift your body into healing mode. Here’s what could be keeping you stuck: • Why chronic stress and nervous system dysregulation can block healing—even when everything else is “on point” • How your nervous system impacts your gut, hormones, metabolism, immune system, and weight • The difference between feeling “tired but wired” vs. true resilience and what a regulated system actually looks like • Simple, science-backed ways to regulate your nervous system through blood sugar, breath, sleep, and daily habits You can’t out-supplement or out-diet a body that feels unsafe. But when you learn how to regulate your nervous system, you unlock your body’s natural ability to repair, rebalance, and heal. Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year. Have a question you’d love answered on Office Hours? Submit it here (0:00) Nervous system regulation, chronic stress, and healing (2:21) Simplifying the nervous system and resilience (4:06) Signs and effects of nervous system dysregulation (6:24) Characteristics of a regulated nervous system (7:39) Practical tips for nervous system regulation (10:09) Building muscle, improving sleep, and myths about regulation (12:20) Upcoming episode and sympathetic activation (14:09) Mitochondrial dysfunction and importance in health (18:37) Closing remarks and call to action
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    20 mins
  • NBA Legend Chris Paul on Longevity, Nutrition & Staying Elite at 40

    NBA Legend Chris Paul on Longevity, Nutrition & Staying Elite at 40
    Apr 8 2026
    Longevity isn’t just about talent—it’s about what you’re willing to change when your body starts asking for something different. On this episode of The Dr. Hyman Show, I’m joined by Chris Paul—one of the most respected point guards of all time—to talk about the mindset that’s carried him through more than two decades in the NBA. We get into what shifted along the way and what it really takes to keep showing up at a high level year after year. Watch the full conversation on YouTube, or listen wherever you get your podcasts. Here’s what we cover: • Why what worked in your 20s stops working and what to do instead • How inflammation shows up and what improves when you address it • Why stress and poor sleep quietly drain energy and slow recovery • What simple habits actually move the needle over time • How understanding your data helps you make better daily decisions Your body is always giving you signals. The earlier you begin to listen and respond, the more it can support you over time. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Sunlighten, Korrus, Seed, Paleovalley, Pique and Made In Cookware. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Visit Korrus.com/DrHyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to paleovalley.com/hyman to save 15% off your first order today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Visit MadeInCookware.com and use code HYMAN10 for 10% off your order. (0:00) Chris Paul’s mindset, falling in love with monotony, and introduction by Dr. Mark Hyman (2:51) Chris Paul on hard work, success, and his grandfather’s influence (9:26) Longevity in the NBA, transition to plant-based diet, and dietary impact on performance (18:21) Effects of diet on performance, recovery, and family health habits (22:11) Impact of diet on athletic performance and Function Health insights (25:26) Emotional and family impact of health changes (27:52) Stress, gut health, cortisol, and the importance of rest (31:34) NBA players’ health insurance, short careers, and health education (34:52) Function Health’s accessibility and intelligence (37:32) Daily routines, hydration, and rest for athletes (45:06) Evolution of Chris Paul’s diet, recovery, and disconnecting from technology (48:24) The significance of sleep for athletes (52:42) Chris Paul’s nonprofit work and food access initiatives (55:00) Future plans, community, accountability, and health advice to a younger self
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    1 hr and 4 mins
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