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Some Work, All Play

Some Work, All Play

By: David Roche and Megan Roche
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Five to ten topics, sometimes about running, with lots of love and enthusiasm and science. We dig deep into training, races, studies, pop culture, and much more! With Megan Roche, M.D. and David Roche!David Roche and Megan Roche Running & Jogging
Episodes
  • 313. Marathons v. Ultras, Fatigue Resistance Debates, Gene Editing Breakthrough, and Posture Impact on Blood Volume!
    Jun 2 2026

    We put some cinder blocks under the head of our bed (for science!) before this great episode. A weird study just came out finding that head-up sleeping may increase red blood cell totals. We talk about what it means and what it doesn’t mean. Excuse us while we launch a cinderblock start-up.

    We also discussed a breakthrough in gene editing for cholesterol, and what that could mean for the future. The world is going to be so different in 50 years! Maybe by then, David can use CRISPR to be able to pronounce science words.

    And this one was full of fun topics! Other topics: our training log discussions, iron levels in athletes, breaking news on heat training from Unbound 200, a science debate on fatigue resistance terminology, and a study on glucose v. fructose.

    Plus, we answer questions on heat training in the car, clean sport for age group athletes, marathon v. ultra training, and health uncertainty.

    You’re going to learn a lot about what Megan would do for 40 grams of carbs. Totally normal stuff if you ask her!

    We love you all! HUZZAH!

    -David and Megan

    Click "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swap

    Buy Janji's amazing gear: https://janji.com (code "SWAP")

    20% flash deal for the Wahoo Kickr Run treadmill on Wednesday: https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buy (code “SWAP”)

    For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap

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    1 hr and 34 mins
  • 312. How Blood Volume Impacts Performance and Adapts Fast, The Scary Potential of Lactate Supplementation, The True GOAT, and The Circle Pit!
    May 26 2026

    We basked in some amazing news before this great episode! The main topic was a breakdown of one of the most important elements of performance and health: blood volume.

    Studies show that blood volume can seem to act as a synonym for fitness, with one finding that 6 weeks of training gains can be reversed with a phlebotomy that returns blood volume to baseline levels. Positive adaptations can happen in a few days, and it clearly matters for performance. If any other intervention worked like that, you’d assume everyone would be talking about it all the time. But blood volume is not discussed often! We pull back the curtain on the science.

    We also talked about a new review article on exogenous lactate supplementation. It might be a brave new world in the next 5 years, but right now there are more questions than answers. We speculate!

    And this one was full of cool topics! Other topics: the shockingly good news Megan has received in recent heart tests, our disdain for the Enhanced Games, recent age group doping news, the Satisfy Circle Pit, the true GOAT of endurance, running v. biking, uphill treadmill workouts, and lots more.

    Yes, David actually hit himself for a joke on this episode. Podcasts are definitely the medium for physical and visual comedy.

    We love you all! HUZZAH!

    -David and Megan

    Click "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swap

    Buy Janji's amazing gear: https://janji.com (code "SWAP")

    The Wahoo KICKR Run is the best treadmill on the market: https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buy (code “SWAP”)

    For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap

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    1 hr and 23 mins
  • 311. The Science Episode! How To Stop Cramps, Fat Oxidation Changes, Missing Link Heat Training, The Difficulty of Physiology Data, and More
    May 19 2026

    We talked about some of the strangest and coolest research topics in endurance sports for this episode! Basically, the science discussions went long, so we just ran with it.

    The main discussion was on how to stop cramps, laying out 10 theories. But put on your tin foil hats, because we think the cramping conspiracy runs deep. Our theory: cramping is connected to fatigue resistance is connected to all endurance performance, and thinking about cramp prevention might revolutionize all training theory even for athletes who never cramp. IT GOES DEEP!

    We also talked about a new missing link heat study, connecting altitude blood changes to long-term passive heat training. It was especially weird because the researchers were unsure of exactly why it happened. Those are the most fun study moments!

    Other topics: very short-term changes in fat max and fat oxidation (featuring the wildest figure we have seen in a long time), the difficulty of studies due to large error bars and small effect sizes, the crossover point in metabolic research, the incredible Dark Wizard documentary, and a question on relationships.

    For a clue about what was censored, here’s the hint: I caught mommy [bleeping] [bleepa blaus].

    We love you all! HUZZAH!

    -David and Megan

    Click "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swap

    Buy Janji's amazing gear: https://janji.com (code "SWAP")

    The Wahoo KICKR Run is the best treadmill on the market: https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buy (code “SWAP”)

    For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap

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    1 hr and 42 mins
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