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Signal and Symptoms Podcast

Signal and Symptoms Podcast

By: Harvey Castro MD Junaid Kalia MD & Edward Marx
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Summary

Three healthcare AI experts who've watched millions wasted on failed projects. Dr. Harvey Castro, Dr. Junaid Kalia, Edward Marx, and guest experts cover all things healthcare AI - from digital transformation to clinical reality. Every Tuesday, we diagnose real failures, reveal what actually works, and help you avoid the expensive mistakes we've seen repeated everywhere. Because when AI decisions affect patient care, getting it right isn't optional.Copyright 2026 Harvey Castro MD, Junaid Kalia MD, & Edward Marx Hygiene & Healthy Living Physical Illness & Disease Politics & Government
Episodes
  • Why Will Digital Twins Change the Way We Treat Patients?
    May 5 2026

    What if the most powerful diagnostic tool wasn't a scan or a lab result — but a continuously learning model of your patient, built from their own data?

    In this episode, Dr. Junaid Kalia sits down with co-host Dr. Harvey Castro, this time in the guest seat, to unpack one of the most transformative concepts in modern medicine: the healthcare digital twin. They trace how the concept evolved from NASA simulations and factory floors into clinical reality, breaking it down clearly for those new to the idea while grounding it in real applications — predictive analytics, personalized pharmacogenomics, and Harvey's personal digital twin, which he built and uses today. They also don't shy away from the harder questions: data privacy, implementation costs, the global adoption gap, and the tension between rapid innovation and regulation that can barely keep pace.

    Whether you're a clinician thinking about what's next for patient care, or a healthcare enthusiast trying to make sense of where medicine is heading, this episode gives you a grounded, honest look at a technology that's closer than you think.

    What You Will Discover:

    - Intro: What Are Healthcare Digital Twins?

    - The Human + AI Concept: Harvey's Personal Digital Twin

    - Top 3 Applications for Digital Twin Transforming Patient Care

    - Data Privacy and Cybersecurity Risks

    - Why Culture Is the Real Rate-Limiting Step

    - Implementation Challenges in the US vs. Other Countries

    - Are Tokens Reliably Used in Healthcare?

    - Genetics, Epigenomics & the Future of Point-of-Care Treatment

    - The Future We're Building: A Final Word from Two Doctors

    Resources:

    🔗 Ask Harvey a healthcare AI question –– https://harvey.deepfoundai.com/

    Connect with us:

    Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

    💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

    🔗Website - https://www.junaidkalia.com/

    📹YouTube - https://www.youtube.com/@junaidkaliamd

    Dr. Harvey Castro, ER Physician, #DrGPT™

    💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

    🔗Website - https://www.harveycastromd.com/

    📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

    📑 Substack - https://harveycastromd.substack.com/

    Edward Marx, CEO, Advisor

    💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

    🔗Website - https://www.marxadvisory.com/

    📹YouTube - https://www.youtube.com/@EdwardMarx

    Visit our website:

    https://signalandsymptoms.com/

    Get advisory insights about Healthcare AI — at zero cost:

    https://junaidkaliamd.substack.com/

    Show More Show Less
    19 mins
  • What Happens to Hospital Revenue When AI Replaces Primary Care?
    Apr 28 2026

    Most healthcare conversations stop at disruption, but this one starts there.

    In this episode, three healthcare experts sit down to map what happens when AI doesn't just change clinical workflows — it rewires the economics behind them. From the slow-adoption trap crippling hospital governance, to the cultural lag quietly signaling a broken system, to a collapse of the referral pipeline impacting financial stability — the kind of conversation most boardrooms aren't having yet.

    The twin disruption isn't coming. It's already restructuring the room. Where do you stand?

    What You Will Discover:

    - Intro: The Twin Disruption No One's Naming

    - Slow Adoption Is Now a Liability

    - Culture Is the Real Bottleneck

    - Will Hospitals Need to Sell Off Physical Assets?

    - On Restructuring Value-Based Care

    - The Shift to 'Tokenized Economy’ in Healthcare

    Referenced in the show:

    🖇️ "The Twin Disruption: How AI is Rewriting the Economics of Healthcare" – https://drive.google.com/file/d/1dGc9RXPlnpZTbs0VEvWJdrDH-0PCEttP/view?usp=sharing

    Connect with us:

    Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

    💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

    🔗Website - https://www.junaidkalia.com/

    📹YouTube - https://www.youtube.com/@junaidkaliamd

    Dr. Harvey Castro, ER Physician, #DrGPT™

    💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

    🔗Website - https://www.harveycastromd.com/

    📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

    📑 Substack - https://harveycastromd.substack.com/

    Edward Marx, CEO, Advisor

    💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

    🔗Website - https://www.marxadvisory.com/

    📹YouTube - https://www.youtube.com/@EdwardMarx

    Visit our website:

    https://signalandsymptoms.com/

    Get advisory insights about Healthcare AI — at zero cost:

    https://junaidkaliamd.substack.com/

    Show More Show Less
    18 mins
  • The Business Playbook for Physicians Who Want to Win Beyond the Clinic
    Apr 21 2026

    You went into medicine to save lives. But somewhere between residency and the real world, you started wondering — is there more I could be doing?

    That question is not a distraction. It might be your next diagnosis, and the biggest obstacle is knowing where to start.

    In this episode, host Dr. Junaid Kalia sits down with Dr. Sara Rana, a physician-turned-venture capitalist and MD-MBA, who saw the gap between healthcare and finance firsthand and built her career bridging it. The conversation moves from her origin story into the practical frameworks, honest realities, and hard-earned wisdom any physician can act on today.

    What You Will Discover:

    - Intro: Dr. Sara’s Origin Story

    - Why Physicians Must Speak Business

    - Charting Her Own Path as Venture Capitalist

    - Inflation, AI & the Forces Reshaping Financial Future

    - Does Race & Gender Matter?

    - 4 Entry Points to Entrepreneurship

    - The Advice That Reframes the Struggle

    [17:23] Does Geography Make or Break You?

    The same disruption reshaping healthcare through AI is exactly why physicians can no longer afford to only speak medicine. This conversation is where that journey begins.

    Connect with us:

    Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

    💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

    🔗Website - https://www.junaidkalia.com/

    📹YouTube - https://www.youtube.com/@junaidkaliamd

    Dr. Harvey Castro, ER Physician, #DrGPT™

    💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

    🔗Website - https://www.harveycastromd.com/

    📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

    📑 Substack - https://harveycastromd.substack.com/

    Edward Marx, CEO, Advisor

    💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

    🔗Website - https://www.marxadvisory.com/

    📹YouTube - https://www.youtube.com/@EdwardMarx

    Special Guest:

    Sara Rana, MD, MBA

    💼LinkedIn - https://www.linkedin.com/in/sararana/

    Visit our website:

    https://signalandsymptoms.com/

    Get advisory insights about Healthcare AI — at zero cost:

    https://junaidkaliamd.substack.com/

    Show More Show Less
    20 mins
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