Welcome to Pulse: Amplify, where we sit down with the leaders and changemakers shaping the future of health.

In this episode Louise and George sit down with Dr Mehmood Khan, CEO of Hevolution Foundation, and Her Royal Highness Princess Dr Haya Bint Khaled Bin Bandar Al Saud, Senior Vice President of Research at Hevolution. Based in Riyadh and backed by Saudi Arabia's Vision 2030, Hevolution is the world's largest philanthropic funder of healthspan science, with over USD $400 million allocated in just three years.

Timed with the release of the second edition of Hevolution's Global Healthspan Report - the most comprehensive look at the field across 23 countries - this conversation moves beyond the longevity hype to explore what it takes to extend healthy human life for the benefit of all.

In this episode:

• Healthspan, not longevity - Why Hevolution is focused on keeping people physically, mentally, and financially independent, and why a global non-profit is the right vehicle for a challenge governments and private enterprise can't tackle alone.
• Why Saudi Arabia, why now - Princess Dr Haya on the demographic shift driving the kingdom's leadership, and why a young population on the brink of ageing is uniquely placed to redesign systems before they break.
• The science that has scientists excited - GLP-1 agonists, senotherapeutics, CRISPR, and cellular reprogramming, and why the real breakthrough is the convergence of these fields, not any one of them in isolation.
• A jaw-dropping case study - Dr Khan walks through how rejuvenating aged liver cells eliminated chronic Hepatitis B in animal models, with first-in-human trials now underway. A profound example of aging biology rewriting the rules for treating incurable diseases.
• What clinicians need to know - Two-thirds of healthcare professionals are now getting monthly healthspan questions from patients. Princess Dr Haya on the shift from reactive to proactive care, and the urgent need for evidence-based healthspan protocols.
• A message for policymakers - Why the Minister of Finance, not just the Minister of Health, needs to be at the table, and why retirement, education, and workforce policies built for a 1%-over-65 world are catastrophically out of date.
• Where digital health innovators should be looking - The five years that could be cut from drug development with better data tools, the four proven interventions that lend themselves to digital monitoring, and why we already have the technology - just not the policy frameworks to deploy it.

Connect with Hevolution on LinkedIn

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This week on Pulse: Hot Topics, Louise and George explore five major developments shaping the future of healthcare.

Microsoft Opens the Lid on How the Public Uses AI for Health — A new Nature Health paper analysing over 617,000 de-identified Copilot health conversations shows nearly one in five are personal health queries, they spike at night when traditional care isn't available, and one in seven are asked on behalf of someone else.

Reddit as a Pharmacovigilance Signal — University of Pennsylvania researchers mined 400,000+ Reddit posts from people taking GLP-1s like Ozempic and Wegovy, surfacing side effects not well captured in trials or drug labelling and revealing a real-time, patient-generated pharmacovigilance system hiding in plain sight.

Apple Walks Into the Radiology Reading Room — Apple's new Studio Display XDR has received FDA clearance for diagnostic radiology at roughly a third of the price of traditional diagnostic monitors, fundamentally changing the economics of building and scaling reading rooms.

US Digital Health VC — AI Is Now the Operating Environment — Silicon Valley Bank and Rock Health data show AI captured nearly half of all healthcare investment in 2025, with Rock Health retiring its "AI deal" tracking category because AI is now table stakes.

The Fourth Wave of Wearables — Bioforecasting — A small study in the European Heart Journal — Digital Health used smartwatch data to predict vasovagal syncope minutes before it happened, signalling a shift from wearables that measure the present to wearables that anticipate what's coming.

Resources:

• Microsoft Copilot Health Queries Study, Nature Health Link
• Reddit GLP-1 Side Effects Study, Nature Health Link
• Apple Studio Display XDR Announcement Link
• Apple White Paper: Reimagining Medical Imaging Link
• SVB 2026 Healthcare Investments & Exits Report Link
• Rock Health Q1 2026 Funding Overview Link
• Prediction of Vasovagal Syncope using AI-enabled Smartwatch PPG, EHJ — Digital Health Link
• Digital Health Workforce Census (opens 1 May, ANZ) — Link

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Production by Octopod Productions | Ivan Juric

Welcome to Pulse: Amplify, where we sit down with the leaders and changemakers shaping the future of health.

In this episode Louise and George sit down with Associate Professor Kudzai Kanhutu to explore one of the most profound questions facing healthcare today: what happens to clinician identity, power, and learning when AI becomes part of the team?

We discuss:

• Why clinician identity is the real conversation behind AI adoption
• What a coaching culture actually requires in a hierarchical, time-poor health system
• The gap between compliance-driven AI and genuinely personalised clinical decision support
• Kudzai's vision for AI as a 360-degree professional mirror - drawing on real outcomes data, not vibes
• The COVID lesson: creativity flourishes when compliance is no longer enough
• Why C-suite AI decisions need to be prefaced with a standing invitation to say "you got it wrong"
• Final thoughts: the world doesn't have to end in AI

Connect with Kudzai: LinkedIn

Visit Pulse+IT.news to subscribe to breaking digital news, weekly newsletters and a rich treasure trove of archival material. People in the know, get their news from Pulse+IT – Your leading voice in digital health news.

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Send us your questions pulsepod@pulseit.news

Production by Octopod Productions | Ivan Juric