• David Cross: The End of the Beginning
    May 28 2026

    Rob and David both hiked Machu Picchu! The “Arrested Development” star and comedian David Cross joins Rob Lowe to discuss his experience in Peru with Bob Odenkirk, whether the best decade was the ’80s or ’90s, a quote from Winston Churchill, his new stand-up special, and much more.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    48 mins
  • Gabriel Iglesias: The Merch Master (Re-Release)
    May 25 2026

    This week, we're looking back at Rob's 2021 conversation with the hilarious Gabriel Iglesias! The comedian joins Rob to discuss Tik Tok, compare notes on doing Family Guy, working with Steven Soderbergh, and Gabriel takes Rob on a virtual tour of an unusual collection. This episode originally aired in April 2021. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    52 mins
  • Will Forte: One Cool Kid Away
    May 21 2026

    Actor and “SNL” alum Will Forte joins Rob Lowe to discuss the release of the long-awaited “Coyote vs. Acme” movie, their animated “Miami Vice” parody from years ago, and the advice they have received from acting greats. Will also shares why raising awareness for Huntington’s disease is a cause close to his heart. Plus, stay tuned for a special surprise cameo.

    To find out more about Huntington’s disease, visit www.honestlyhd.com.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    1 hr and 4 mins
  • Josh Groban: A Beard Is Contour for Men
    May 14 2026

    Singer, songwriter, actor, and Dodgers super-fan Josh Groban joins Rob Lowe to discuss recording a song with his father for his new album, what it’s really like to perform the National Anthem at a baseball stadium, exchanging letters with musical theater legend Stephen Sondheim, his thoughts on the most recent Coachella music festival, and much more. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    45 mins
  • Paris Hilton: I'm So Happy (Re-Release)
    May 11 2026

    This week, we’re looking back on Rob’s interview with the multi-talented Paris Hilton! The two talked travel, growing up in front of the camera, retiring from clubbing, the Metaverse and her documentary "This is Paris.” This episode came out in June 2022.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    45 mins
  • Maury Povich: On Par
    May 7 2026

    Rob and Maury Povich are kindred spirits! The legendary broadcaster, best known for hosting the long-running talk show "Maury," joins Rob Lowe to discuss his new podcast, his wife, Connie Chung, his coverage of Rob back in the day, his good friend President George W. Bush and much more. This episode was recorded on April 17th. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    51 mins
  • Ellen Burstyn: Stop Acting
    Apr 30 2026

    Rob is honored to be joined by Ellen Burstyn today! Legendary actress Ellen Burstyn (The Exorcist, Interstellar, The Last Picture Show, Requiem for a Dream) joins Rob Lowe to discuss the poem that saved her life, memories from shooting The Exorcist, her secrets to staying sharp at 93 years old, life-changing lessons from the genius acting teacher Lee Strasberg, handpicking Martin Scorsese for an early film, movie star jail, and much more. This episode is brought to you by Macy's
    macys.com/giftguide. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    49 mins
  • Clint and Ron Howard: If You Love It (Re-Release)
    Apr 27 2026

    This week, we're looking back at Rob's 2021 conversation with Ron and Clint Howard! The brothers discuss family, creativity, and Hollywood in this wide-ranging conversation. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    1 hr and 9 mins