Episodes

  • Naveed Sattar on early, large-scale weight loss & the future of type 2 diabetes care, Laurent Azoulay on GLP-1s & the risk for optic neuropathy, plus a classic edition of "Rapid Exchange."

    Naveed Sattar on early, large-scale weight loss & the future of type 2 diabetes care, Laurent Azoulay on GLP-1s & the risk for optic neuropathy, plus a classic edition of "Rapid Exchange."
    May 4 2026

    Welcome to the latest episode (May 2026) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the May 2026 issue of Diabetes Care and beyond.

    4:45 Alice welcomes Naveed Sattar, MBChB, PhD, Professor of Cardiometabolic Medicine at the University of Glasgow. He is a co-author on the article "Why Early, Large-scale Weight Loss Is the Future of Type 2 Diabetes Care," available for free at doi.org/10.2337/dci25-0069.

    30:05 Mike speaks with ​​Laurent Azoulay, PhD, Associate Professor in the Department of Epidemiology, Biostatistics and Occupational Health and Gerald Bronfman Department of Oncology, McGill University in Montreal, Canada. He is senior author on the article "Glucagon-Like Peptide 1 Receptor Agonists and Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients With Type 2 Diabetes," available for free at doi.org/10.2337/dc25-2577.

    36:15 In this month's "Rapid Exchange" segment, Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2025 issue of Diabetes Care. Studies highlighted in this segment include:

    • Ganeshalingam et al. Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly doi.org/10.2337/dc25-2041

    • Mital et al. Everyone or Just Some? Cost-Effectiveness of General Population Versus Targeted Screening Strategies for Type 1 Diabetes in Canada doi.org/10.2337/dc25-2248

    • Weiskorn et al. Hypercholesterolemia and Lipid-Lowering Therapy in Children and Adolescents With Type 1 Diabetes: Do We Implement Current Guidelines? doi.org/10.2337/dc25-2459

    • Ziegler et al. Effect of High-Dose Oral Insulin in Children With Stage 1 Type 1 Diabetes: The Fr1da Insulin Intervention Randomized Controlled Trial doi.org/10.2337/dc25-2818

    • Harjutsalo et al. Shrunken Pore Syndrome and Risk of Cardiovascular Disease and All-Cause Mortality in Individuals With Type 1 Diabetes With and Without Albuminuria doi.org/10.2337/dc25-2987

    • Maher et al, Screening for Diabetes and Prediabetes in Cystic Fibrosis Using a Nonfasting 50-Gram 1-Hour Oral Glucose Challenge Test doi.org/10.2337/dc25-2806

    To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    50 mins
  • Anna Kahkoska & Medha Munshi on improving care for T1D in older adulthood, Jennifer Sherr on the persistent burden of severe hypoglycemia in people with T1D despite technology use, plus a classic edition of "Rapid Exchange."

    Anna Kahkoska & Medha Munshi on improving care for T1D in older adulthood, Jennifer Sherr on the persistent burden of severe hypoglycemia in people with T1D despite technology use, plus a classic edition of "Rapid Exchange."
    Apr 2 2026
    Welcome to the latest episode (April 2026) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2026 issue of Diabetes Care and beyond. 4:35 Alice welcomes Anna Kahkoska, MD, PhD, assistant professor in the Department of Nutrition and Department of Medicine at the University of North Carolina at Chapel Hill, as well as Medha Munshi, MD, director of the Joselyn Geriartic Diabetes Program and professor of medicine at Harvard Medical School. They are lead and senior authors on the article, "Challenges and Opportunities for Improving Care for Type 1 Diabetes in Older Adulthood," available for free at doi.org/10.2337/dci25-0078. 22:00 Mike speaks with ​​Jennifer Sherr, MD, PhD, professor of pediatrics in the Division of Endocrinology and Diabetes at Yale University. She is first author of the article "Persistent Burden of Severe Hypoglycemia and Impaired Awareness of Hypoglycemia Among People With Type 1 Diabetes Despite Technology Use: A Follow-up Survey," available for free at doi.org/10.2337/dc25-2345. 33:10 In this month's "Rapid Exchange" segment, Alice and Mike wrap up the episode by reviewing several interesting articles in the April 2025 issue of Diabetes Care. Studies highlighted in this segment include: Thai et al. Longitudinal Analysis of Liver Chemistry Trajectories and Risk of Type 2 Diabetes in Children With Metabolic Dysfunction–Associated Steatotic Liver Disease: A Multicenter Cohort Study doi.org/10.2337/dc25-1532 Twig et al. Thyroid, Celiac, and Other Autoimmune Diseases and the Risk of Incident Type 1 Diabetes in Young Adulthood doi.org/10.2337/dc25-1423 Van der Meer et al. Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study doi.org/10.2337/dc25-2295 Dumortier et al. Effects of Sodium–Glucose Cotransporter 2 Inhibitor Use on Mortality, Amputation, and Healing in Patients With Diabetic Foot Ulcer doi.org/10.2337/dc25-2001 Retnakaran et al. Impact of an Additional Pregnancy on the Natural History of Insulin Sensitivity, β-Cell Function, and Glycemia in Parous Women doi.org/10.2337/dc25-2354 Godneva et al. Investigating the Spectrum of Normoglycemia: Time in Glycemic Ranges and Their Association With Metabolic Outcomes in Individuals Without Diabetes doi.org/10.2337/dc25-2154 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    50 mins
  • Findings from the 2025 IDF Diabetes Atlas with Felix Teufel, Teplizumab & Type 1 Diabetes Therapies with Chantal Mathieu, and more!

    Findings from the 2025 IDF Diabetes Atlas with Felix Teufel, Teplizumab & Type 1 Diabetes Therapies with Chantal Mathieu, and more!
    Mar 2 2026
    Welcome to the latest episode (March 2026) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2026 issue of Diabetes Care and beyond. 5:45 Alice welcomes Felix Teufel, MD and PhD candidate in global health and development at Emory University's Rollins School of Public Health. He is corresponding author on the article, "Global, Regional, and National Estimates of Undiagnosed Diabetes in Adults: Findings From the 2025 IDF Diabetes Atlas," available for free at doi.org/10.2337/dc25-2583. 18:25 Mike speaks with Chantal Mathieu, MD, PhD, professor of medicine at the Katholieke Universiteit Leuven in Belgium and chair of endocrinology at the University Hospital Gasthuisberg Leuven. She is corresponding author on the article "Toward Disease-Modifying Therapies in Type 1 Diabetes: Focus on Teplizumab," available for free at doi.org/10.2337/dci25-0066. 45:55 In this month's "Diabetes Care Rapid Exchange" segment, Alice and Mike wrap up the episode by reviewing several interesting articles in the March 2025 issue of Diabetes Care. Studies highlighted in this segment include: Jacobsen et al. Going From Stage 2 to Stage 3 Type 1 Diabetes—Does Not Matter How You Got Here doi.org/10.2337/dci25-0118 Kuo et al. The Effect of Midpregnancy Screening for Gestational Diabetes Mellitus on Pregnancy Outcomes: The TESGO Randomized Controlled Trial doi.org/10.2337/dc25-0084 Moscoso-Vasquez et al. Safety and Feasibility of a Fully Automated Insulin Delivery System: FCL@Home, a Multicenter Randomized Clinical Trial in Individuals With Type 1 Diabetes doi.org/10.2337/dc25-1526 Di Marco et al. Metabolic Factors Modulating the Connection Between Diabetes and Pulmonary Alterations doi.org/10.2337/dc25-2334 Matus et al. Interoceptive Awareness Moderates the Relationship Between Hypoglycemia Exposure and Symptom Recognition in Adults With Type 1 Diabetes doi.org/10.2337/dc25-2242 Wang et al. Impact of Maternal Diabetes in Pregnancy on Newborn IgG Antibody Repertoire and Infection Risk in the First 6 Months of Life doi.org/10.2337/dc25-0990 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    1 hr and 2 mins
  • Untold Histories of Diabetes with Vanessa Heggie, Differential Longitudinal Effects of Glucose-Lowering Medications on Glucagon and C-peptide Responses in the Glycemia Reduction Approaches in Diabetes with Steven Kahn, and more!

    Untold Histories of Diabetes with Vanessa Heggie, Differential Longitudinal Effects of Glucose-Lowering Medications on Glucagon and C-peptide Responses in the Glycemia Reduction Approaches in Diabetes with Steven Kahn, and more!
    Feb 5 2026
    Welcome to the latest episode (February 2026) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the February 2026 issue of Diabetes Care and beyond. 4:00 Mike and Alice discuss a unique article from this month's issue entitled "New Perspectives: Four Unsung Heroes of Diabetes Research," which gives a historical account of diabetes through four lesser known stories. They are joined by author Vannesa Heggie, FRHS, FHEA, Associate Professor of the History and Science and Medicine at the University of Birmingham. This article is available for free at doi.org/10.2337/dci25-0055. 13:50 Mike speaks with Steven E. Kahn, MB, ChB, Professor of Medicine Division of Metabolism, Endocrinology and Nutrition at the University of Washington (UW) Department of Medicine, as well as Director of the Diabetes Research Center at UW and Editor-in-Chief of Diabetes Care. He is the lead author of "Differential Longitudinal Effects of Glucose-Lowering Medications on Glucagon and C-peptide Responses in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE)," available for free at doi.org/10.2337/dc25-2186. 28:40 In the "Diabetes Care Rapid Exchange," Alice and Mike wrap up the episode by reviewing several interesting articles in the February 2025 issue of Diabetes Care. Studies highlighted in this segment include: Odegaard et al. The Effect of Substituting Water for Artificially Sweetened Beverages on Glycemic and Weight Measures in People With Type 2 Diabetes: The Study of Drinks With Artificial Sweeteners (SODAS), a Randomized Trial doi.org/10.2337/dc25-1516 Josefson et al. Midchildhood Obesity After Exposure to Gestational Diabetes Mellitus: The SWIFT Study in Youth doi.org/10.2337/dc25-1093 Wagner et al. Beyond Glucose—Rethinking Prediabetes for Precision Prevention doi.org/10.2337/dci25-0054 Wang et al. Gestational Diabetes Mellitus and Accelerated Biological Aging in Middle-Aged and Elderly Women doi.org/10.2337/dc25-1842 Santos-Pardo et al. Coronary Stent Failure in Patients With Diabetes: A Nationwide Observational Study From SWEDEHEART doi.org/10.2337/dc25-1624 Yu et al. Reproductive Lifespan and Reproductive Factors in Relation to Dementia Risk in Postmenopausal Women With Type 2 Diabetes doi.org/10.2337/dc25-1961 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    45 mins
  • "How to Fix a Broken Healthcare System" with Seth Berkowitz, Marshall Chin, and Mariana Socal, a classic Rapid Exchange, and more!

    "How to Fix a Broken Healthcare System" with Seth Berkowitz, Marshall Chin, and Mariana Socal, a classic Rapid Exchange, and more!
    Jan 6 2026
    Welcome to the latest episode (January 2026) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the January 2026 issue of Diabetes Care and beyond. 3:40 In a special segment, Mike and Alice are joined by three speakers from the Diabetes Care Symposium "How to Fix a Broken Healthcare System," presented at the ADA Scientific Sessions last June. They're joined by Seth Berkowitz, MD, MPH, associate professor in the Division of General Medicine and Clinical Epidemiology at the University of North Carolina at Chapel Hill School of Medicine, Marshall Chin, MD, MPH, general internist at the University of Chicago, and Mariana Socal, MD, PhD, MPP, MSc, associate professor in the Department of Health Policy and Management at Johns Hopkins Bloomberg School of Public Health. What's Keeping the U.S. From Better Population Health? doi.org/10.2337/dci25-0003 Improving Affordability of Pharmaceutical Treatments for Diabetes: A Call for Action doi.org/10.2337/dci25-0002 How to Fix a Broken Health Care System: Pathways to Maximize Health and Well-being for All doi.org/10.2337/dci25-0001 33:25 In the "Diabetes Care Rapid Exchange," Alice and Mike wrap up the episode by reviewing several interesting articles in the January 2025 issue of Diabetes Care. Studies highlighted in this segment include: Snaith et al. Tirzepatide in Adults With Type 1 Diabetes: A Phase 2 Randomized Placebo-Controlled Clinical Trial doi.org/10.2337/dc25-2379 Park et al. Sodium–Glucose Cotransporter 2 Inhibitors, Glucagon-Like Peptide 1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes doi.org/10.2337/dc25-1031 Wilson, et al. Use of Teplizumab to Modulate Stage 2 Type 1 Diabetes in Two Individuals With Autoimmune Polyendocrine Syndrome 1 doi.org/10.2337/dc25-1444 Li et al. Prediction of Weight Loss and Regain Based on Multiomic and Phenotypic Features: Results From a Calorie-Restricted Feeding Trial doi.org/10.2337/dc25-0728 Von Conta et al. Advancing Continuous Glucose Monitoring for Inpatient Clinical Decision Support: Individual Algorithmic Mean Absolute Relative Difference doi.org/10.2337/dc25-1494 Lehmann et al. Listening to Hypoglycemia: Voice as a Biomarker for Detection of a Medical Emergency Using Machine Learning doi.org/10.2337/dc25-1680 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    49 mins
  • Diana Sherifali & Megan Racey on type 2 diabetes remission, Vivian Fonseca on inadequately controlled t2d and hypercortisolism, and more!

    Diana Sherifali & Megan Racey on type 2 diabetes remission, Vivian Fonseca on inadequately controlled t2d and hypercortisolism, and more!
    Dec 5 2025
    Welcome to episode no. 40 (December 2025) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the December 2025 issue of Diabetes Care and beyond. 4:10 Alice is joined by Diana T. Sherifali, PhD, BScN, Professor in the School of Nursing at McMaster University and lead of the McMaster Evidence Review & Synthesis Team (MERST), as well as Megan Racey, PhD, Senior Research Coordinator at MERST. Their article, "Type 2 Diabetes Remission: A Systematic Review and Meta-analysis of Nonsurgical Randomized Controlled Trials," is available for free at doi.org/10.2337/dc25-0562 22:25 Mike speaks with Vivian A. Fonseca, MD, FRCP, Assistant Dean for Clinical Research at the Tulane University School of Medicine. His article, "Inadequately Controlled Type 2 Diabetes and Hypercortisolism: Improved Glycemia With Mifepristone Treatment," is available for free at doi.org/10.2337/dc25-1055. 38:35 In the "Diabetes Care Rapid Exchange," Alice and Mike wrap up the episode by reviewing several interesting articles in the December 2025 issue of Diabetes Care. Studies highlighted in this segment include: Becker et al. Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment doi.org/10.2337/dc25-1195 Sacre et al. Incidence of Type 2 Diabetes With Verapamil Compared With Other Calcium Channel Blockers doi.org/10.2337/dc25-1440 Wang et al. Response to Comment on Wang et al. Transition of BMI Status From Childhood to Adulthood and Cardiovascular-Kidney-Metabolic Syndrome in Midlife: A 36-Year Cohort Study. Diabetes Care 2025;48:2045–2053 doi.org/10.2337/dci25-0102 Hirsch et al. Adults With Type 2 Diabetes Benefit From Automated Insulin Delivery Irrespective of C-Peptide Level doi.org/10.2337/dc25-1125 Pop-Busui et al. Screening Natriuretic Peptide Levels Predicts Heart Failure and Death in Individuals With Type 1 and Type 2 Diabetes Without Known Heart Failure doi.org/10.2337/dc25-1260 Fang et al. Risk of Acute Pancreatitis and Biliary Events After Initiation of Incretin-Based Medications in Patients With Type 2 Diabetes doi.org/10.2337/dc25-1840 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    56 mins
  • Inês Barroso on undiagnosed G6PD deficiency in Black and Asian individuals, Kirsten Nørgaard on upper-limb complications in diabetes, and more!

    Inês Barroso on undiagnosed G6PD deficiency in Black and Asian individuals, Kirsten Nørgaard on upper-limb complications in diabetes, and more!
    Nov 6 2025
    Welcome to episode no. 39 (November 2025) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the November 2025 issue of Diabetes Care and beyond. 3:00 Alice is joined by Inês Barroso, PhD, MSc, Professor of Diabetes at the University of Exeter Medical School. She is the senior author of the article "Undiagnosed G6PD Deficiency in Black and Asian Individuals Is Prevalent and Contributes to Health Inequalities in Type 2 Diabetes Diagnosis and Complications," available for free at doi.org/10.2337/dc25-0556. 22:35 Mike speaks with Kirsten Nørgaard, MD, DMSc, a Clinical Professor of Medicine in the Steno Diabetes Center at the University of Copenhagen in Denmark. She is the senior author of the article "Upper-Limb Complications in Diabetes: A Narrative Review," available for free at doi.org/10.2337/dci25-0012. 34:40 In the "Diabetes Care Rapid Exchange," Alice and Mike wrap up the episode by reviewing several interesting articles in the November 2025 issue of Diabetes Care. Studies highlighted in this segment include: Rossing et al. Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis doi.org/10.2337/dc25-0472 Nash et al. Reimagining Acute Diabetes Care: Insights From the Victorian Virtual Emergency Department doi.org/10.2337/dc25-0852 Pop-Busui et al. Differences in Prevalence and Incidence of Electrocardiogram Abnormalities and Cardiovascular Autonomic Neuropathy Among Randomized Glucose-Lowering Treatments in Early Type 2 Diabetes: The Glycemia Reduction Approaches in Diabetes (GRADE) Cohort doi.org/10.2337/dc25-1087 Ayati et al. Quantifying Barriers to Diabetic Eye Screening: A Two-Center Study at the University of California doi.org/10.2337/dc25-0951 Agarwal et al. Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial) doi.org/10.2337/dc25-1673 Applebaum et al. Risk Factors and Consequences of Lapses in Proliferative Diabetic Retinopathy Care in a National Cohort doi.org/10.2337/dc25-1202 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    50 mins
  • Carmella Evans-Molina on the heterogeneity of type 1 diabetes, Samuel Seidu with an observational study on older adults with type 2 & the risk of falls, and more!

    Carmella Evans-Molina on the heterogeneity of type 1 diabetes, Samuel Seidu with an observational study on older adults with type 2 & the risk of falls, and more!
    Oct 3 2025
    Welcome to episode no. 38 (October 2025) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the October 2025 issue of Diabetes Care and beyond. 2:11 Mike is joined by Carmella Evans-Molina, MD, PhD, the Eli Lilly Professor of Pediatric Diabetes at Indiana University, where she is Director of the Indiana Diabetes Research Center. She is first author on the article "The Heterogeneity of Type 1 Diabetes: Implications for Pathogenesis, Prevention, and Treatment—2024 Diabetes, Diabetes Care, and Diabetologia Expert Forum," available for free at doi.org/10.2337/dci25-0013. 18:15 Alice speaks with Professor Samuel Seidu from the Diabetes Research Centre at the University of Leicester in the U.K. His article, "Glucose Control, Sulfonylureas, and Insulin Treatment in Older Adults With Type 2 Diabetes and Risk of Falls and Fractures: An Observational Study," available for free at doi.org/10.2337/dc25-0517. 35:45 In the "Diabetes Care Rapid Exchange," Alice and Mike wrap up the episode by reviewing several interesting articles in the October 2025 issue of Diabetes Care. Studies highlighted in this segment include: Chen et al. Stroke Incidence Evolution in People With Newly Diagnosed Diabetes and Impaired Glucose Tolerance: A 34-Year Follow-up of the Da Qing Diabetes Study doi.org/10.2337/dc24-2675 Thapa et al. Clinical and Demographic Characteristics Associated With Diabetes Remission in Six Integrated Health Care Systems: A Retrospective Cohort Study doi.org/10.2337/dc25-0530 Hong et al. Differential Effect of GLP-1 Receptor Agonists and SGLT2 Inhibitors on Lower-Extremity Amputation Outcomes in Type 2 Diabetes: A Nationwide Retrospective Cohort Study doi.org/10.2337/dc25-0292 Ljungberg et al. Risk of Phimosis Associated With SGLT2i Versus GLP-1RA: A Danish Cohort Study doi.org/10.2337/dc25-0693 Larsson et al. Sight-Threatening Diabetic Retinopathy During and After Pregnancy—A Nationwide Matched-Cohort Study doi.org/10.2337/dc25-0758 Zaharieva et al. Physical Activity Is Associated With Improved Glycemic Outcomes in Newly Diagnosed Youth With Type 1 Diabetes: 4T Exercise Program doi.org/10.2337/dc25-0765 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
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    50 mins