When Kristelle and Evan Shulman lose their young son Noah to a rare mitochondrial disease, they are told they may never be able to have a healthy biologically related child. Then they discover mitochondrial replacement technology, or MRT, a controversial procedure that could prevent the disease from being passed on to future generations. This episode explores how families, clinicians, and policymakers grapple with the ethics of novel reproductive technologies that offer extraordinary hope amid profound uncertainty. (Part 1 of 2.)

This episode features:

Kristelle and Evan Shulman: Parents navigating mitochondrial disease and reproductive decision-making.

Marni Falk, MD: Attending physician and Executive Director of the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia and Professor in the Division of Human Genetics, Department of Pediatrics at the University of Pennsylvania Perelman School of Medicine.

Jeffrey Kahn, PhD, MPH: Andreas C. Dracopoulos Director of the Johns Hopkins Berman Institute of Bioethics.

“playing god?” is a podcast by the iDeas Lab at the Johns Hopkins Berman Institute of Bioethics.

To read a transcript of this episode, visit the iDeas Lab website at https://bioethics.jhu.edu/pgs2e3.

The Johns Hopkins University Sesquicentennial is proud to support this podcast. JHU celebrates 150 years of pioneering education and research—advancing knowledge to meet the challenges of every generation. Learn more at 150.jhu.edu.